INTAVIS relased the InsituStain in November 2006. It is an economical solution for tedious routine work, automating most steps of in situ hybridization and immunohistochemistry. In addition, it is capable of other methods such as gel staining or blot processing. After the merger with Hölle & Hüttner and replacement by the newly developed BioLane HTI 16V, the InsituStain has been discontinued end of 2008.

The InsituStain is capable of automating complex protocols using up to 12 different reagents. Two cooled and two heated buffer positions provide maximum convenience. A selection of optional modules for the InsituStain makes it simple to run different techniques on one system. The modules can be easily swapped from one application to the other.

For in situ detection, the InsituStain automates steps like rehydration, permeation, postfixation and antibody incubation, as well as all washing steps in the procedure. Even hybridization with one single probe or incubation with one single antibody can be performed inside the machine, making it an effective tool for mutant screening. In addition, it allows full recovery of probes and antibodies, even for those used for blot processing.

The system is operated by easy-to-use PC-based software. Methods are generated using the software and transferred to the InsituStain via a standard SD memory card.